“An estimated 86 million girls are now protected against the leading cause of cervical cancer, thanks to a concerted three-year effort by Gavi, the Vaccine Alliance and lower-income countries,” the organisation said.

It added in a statement to mark World Cervical Cancer Elimination Day that “an estimated 1.4 million future deaths” had been prevented.

Cancer caused by HPV disproportionately affects low-income countries, which often lack screening services and access to treatment.

These countries accounted for 90% of the 350,000 cervical cancer deaths recorded in 2022, according to Gavi.

The organisation’s chief executive Sania Nishtar credited the “incredible commitment” by countries and organisations for helping to reach the target of protecting 86 million girls.

Gavi said that across Africa the coverage rate for the vaccine had risen from four percent of girls in 2014 to 44% at the end of 2024, higher than for Europe on 38%.

The alliance said it used economies of scale to bring down prices and make vaccines available to about 50 poorer countries.

“Gavi secured commitments from manufacturers to invest in HPV vaccines – and the price of HPV vaccines in Gavi-supported countries is now between US$2.90 and US$5.18 per dose, compared with US$100 or more elsewhere,” said the statement.

“This collaborative effort is driving major global progress towards eliminating one of the deadliest diseases affecting women,” she said, while stressing that the cancer still kills a woman every two minutes.

The World Health Organization (WHO) officially backed a single-dose HPV vaccination schedule instead of the previous two doses in 2022, allowing twice as many girls to be vaccinated with existing stocks.