The incident began just before 6pm about 14km outside of London, when officers were called for reports of multiple vehicles being fired at on Interstate 75 in Laurel County, multiple media accounts said. The shots were reportedly coming from a wooded area or an overpass.

“Please avoid I-75 around Ext 49. Until further notice! Use alternative route do not be anywhere in that area,” London mayor Randall Weddle said on Facebook.

Police officials said the suspect had not been caught.

Kentucky state trooper Scottie Pennington wrote on Facebook, “The suspect has not been caught at this time and we are urging people to stay inside.”

Kentucky governor Andy Beshear wrote on X: “Kentucky, we are aware of a shooting on I-75 in Laurel County. Please avoid the area. We will provide more details once they are available.”

He also asked that residents “please pray for everyone involved.”

London is a small city of about 8,000 residents, about 161km northwest of the state capital Frankfort.