Griezmann opened the scoring in the sixth minute, slotting in a low shot from the edge of the box before Celtic were reduced to 10 men when forward Daizen Maeda received a straight red card for a studs-up challenge on Atletico defender Mario Hermoso in the 23rd minute.

Morata extended the hosts’ lead with a close-range finish in added time before the break and Griezmann scored the third with a brilliant volley in the 60th minute.

Substitute Samuel Lino netted the fourth with a fine curling strike into the top left corner six minutes later, before Morata blasted home an unstoppable strike from a rebound in the 76th minute and Saul Niguez wrapped up the scoring from close-range in the 85th.

Atletico went top in Group E on eight points with two games remaining, one point ahead of second-placed Lazio who beat Feyenoord 1-0 on Tuesday.

The Dutch side are third on six points with Celtic bottom on one point.