
The Austrian defeated the 21st seed 6-1, 6-2, 6-4 in just 2hr 4min inside Arthur Ashe Stadium.
“I had a great feeling from the first moment on,” said Thiem, gunning for his first Grand Slam title at Flushing Meadows.
“My feeling was that first set, especially until I broke him for the second time, was really intense, very long rallies.
“The first and second set second I guess it looks way easier on the scoresheet than it was actually,” he added.
The 27-year-old Thiem hit 11 aces compared to just one by the 21-year-old de Minaur.
Thiem won a whopping 83% of first serve points, while de Minaur, playing in his first Grand Slam quarter-final, could only manage 49%.
Thiem was able to withstand most of what de Minaur threw at him, getting 81% of returns in.
The powerful Austrian also smashed 44 winners while De Minaur mustered only 17.
Thiem will play third-seeded Russian Daniil Medvedev in the last four for a place in Sunday’s final.
The disqualification of Novak Djokovic for accidentally hitting a line official with a ball during the last 16 means the US Open will crown a first-time Grand Slam winner this year.
Fifth seed Alexander Zverev of Germany faces Spain’s 20th seed Pablo Carreno Busta in the competition’s other semi-final.
The men’s semi-finals take place on Friday.