Six players scored in double figures for the Trail Blazers, who won for the 11th time in their past 15 outings. Jusuf Nurkic had 22 points on 9-for-15 shooting.

DeMar DeRozan scored 35 points, Rudy Gay contributed 25 points and LaMarcus Aldridge collected 17 points and 10 rebounds for the Spurs, who have lost three in a row following a five-game win streak.

Nurkic scored 14 points and Portland shot 60% from the field en route to a 70-57 halftime lead. Aldridge and DeRozan each had 13 points for San Antonio at the break.

The Blazers extended their advantage to 84-63. The Spurs responded with a 25-4 run to tie it at 88-88 late in the third quarter, Gay scoring 16 of the first 18 points in that span. Portland finished the quarter with an 8-2 spurt — Lillard scoring all of the Blazers’ points — to take a 96-90 edge into the final period.

Portland increased its lead to 108-97 on a 3-pointer by McCollum with 7:37 remaining. DeRozan sank a pair at the line to cut it to 108-99, but another trey by McCollum made it 111-99 with seven minutes to play.

The Spurs trimmed the deficit to 120-110 on a 3-pointer by Marco Belinelli with 3:40 to play, but they could get no closer until the closing seconds.

San Antonio jumped to a 21-15 lead, hitting nine of its first 14 shots from the field. The Spurs carried a 34-31 advantage into the second quarter, Aldridge leading the way with 13 points.

Portland jumped in front 51-48 midway through the second quarter, then increased the difference to 67-54 late in the quarter. The Blazers took a 13-point bulge into intermission.